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HPN NAD+ Booster (NAD3), Anti Aging Cell Booster, NRF2 Activator, Nicotinamide Riboside Alternative, NAD Supplement Natural Energy, Longevity, and Cellular Health, 312 Mg per Serving (1 Month Supply)

4.3 4.3 out of 5 stars 3,791 ratings

$37.00 with 5 percent savings $0.62 per Count
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Purchase options and add-ons

Brand HPN
Flavor Unflavored
Unit Count 60.0 Count
Item Form Capsule
Item Weight 2.47 ounces
Product Benefits Anti-Aging, Detoxing, Energy Management, Inflammation Management
Age Range (Description) Adult
Package Information Bottle
Number of Items 60
Servings per Container 30

About this item

  • WHAT IS NAD? - Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found in all living cells. It's a key component for the fundamental biological processes that make life possible. The problem is, as we age, NAD+ levels start to decline. Recent studies have verified there are tremendous health benefits to boosting NAD+
  • BENEFITS OF NAD(3) - NAD(3) impacts all the key areas of cell health: It boosts NAD+ the crucial co-enzyme for Mitochondrial function. Activates Sirtuins, the healthy-aging and survival protein. Increases Telomerase activity to protect DNA. And influences NLRP3 expression to control cellular inflammation
  • THE WORLD’S MOST EFFECTIVE NAD+ BOOSTER – The studies are in & the research is very clear, while nicotinamide riboside is effective, it is not the best cell health product on the market. NAD(3) has advanced the science of NR - and revolutionized health from within
  • THE NEXT EVOLUTION OF HPN’s BEST SELLING PRODUCT - In 2013, High Performance Nutrition released a product that changed everything we thought we knew about anti aging & longevity; NAD(3) is the next, clinically superior evolution
  • INDEPENDENTLY TESTED BY THE BSCG - NAD(3) is made in the USA with NSF cGMP certified manufacturing and independently tested for guaranteed purity and quality with every bottle

Additional Details

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60 Count (Pack of 1)
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$33.59 ($0.56/Count)

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This item: HPN NAD+ Booster (NAD3), Anti Aging Cell Booster, NRF2 Activator, Nicotinamide Riboside Alternative, NAD Supplement Natural Energy, Longevity, and Cellular Health, 312 Mg per Serving (1 Month Supply)
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Product Description

NAD
HOW TO USE

element

Cooper Nictonic Acid: Copper Nicotinic Acid is a special combination of Copper I and Niacin, better known as a Vitamin B3. Copper Nicotinic Acid is shown to boost mental clarity, boost energy levels, and alleviating discomfort by controlling lactic acid levels. More interestingly, this combination has been proven by clinical research to boost NAD+ levels as well, along with providing protection to your stomach lining, boosting your immune system and providing mental clarity.*

element

Theacrine is commonly associated with caffeine for its similar properties but there is one major difference that needs to be addressed. Unlike caffeine, Theacrine has no downside - so you get all the energy output without a crash. In a human study Theacrine users reported an increase in their energy output, it doubled their concentration and boosted their motivation to exercise. Theacrine works by stimulating dopamine production in the brain. Doctors call dopamine the “happiness molecule” because it increases feelings of satisfaction. But dopamine is also the “messenger” of the brain, delivering signals across your neural network. Theacrine can help improve your mood and speed up your mental capacity.*

wasabi

Considered one of the rarest and most valuable perennials on planet earth, Wasabia Japonica is an incredible plant with a laundry list of benefits shown to protect you and your health from degenerative condition. What’s behind this incredible plant? A very unique molecule called 6-(methylsulfinyl)hexyl isothiocyanate, or 6-MITC for short. This molecule is found in low quantities naturally in Wasabi and it has shown to boost anti-inflammatory, antimicrobial, anti-platelet, and potentially anti-cancer properties! NAD3 is formulated with a very exact amount of Wasabi Japonica rich in isothiocyanate. The exact number is a patent-protected trade secret with extensive clinical research. During clinical trials, NAD3 demonstrated a significant boost in NRF-2. Higher NRF-2 can help with reducing inflammation, help stop cancer cells from growing, and have shown to protect you from heart and neurodegenerative conditions.*

happy couple

NAD3
BOOSTING NAD+ IS CRUCIAL TO CELLULAR HEALTH

NAD3 has clinically been shown to increase mitochondrial capacity by 50% over the standard NAD+ booster. NAD3 activates localized mitochondrial sirtuins SIRT3, SIRT4, and SIRT5 which are known to suppress diverse age-related pathologies. Boosting mitochondrial function rejuvenates your cells so they start operating as if they were younger selves again.*

A Theacrine-Based Supplement Increases Cellular NAD+ Levels And Affects Biomarkers Related To Sirtuin Activity in C2C12 Muscle Cells In Vitro

MORE THAN YOUR AVERAGE NAD+ BOOSTER

WHY NAD3?

With our first NAD+ Booster, we helped to create awareness for the benefits of increasing NAD+ levels. After 5 years of continued research and thousands of satisfied customers, there is now little doubt boosting NAD+ levels brings an array of benefits such as better focus and memory, better sleep, more energy, and a faster metabolism.*

Outcomes of NAD3 include:

  • Increases Mitochondrial capacity by 50%*
  • Activates localized Mitochondrial Sirtuins*
  • Control NLRP3 Expression to Reduce Inflammation*
  • Increase NRF-2 Expression for More Antioxidant Absorption*
  • A Theacrine-Based Supplement Increases Cellular NAD+ Levels and Affects Biomarkers Related to Sirtuin Activity in C2C12 Muscle*
 TIMER

THE ANTI-AGING SUPPLEMENT*

The aging process is understood as the unwinding of the double helix structures of our DNA and the shortening of our telomeres as a cell divide. The unwinding of the double helix exposes us to the free radicals we produce as a byproduct of our natural metabolic functions, as well as the toxins and pollutants of our environment: things such as our food, our water, and the air we breathe.*

By activating sirtuins, we can naturally slow the cellular aging process, by performing the function of deacetylation, which protects DNA from toxins, pollutants, and free radicals while also repairing and restructuring the double helix.*

NAD3 has been proven to activate your entire Sirtuin survival protein family enabling your body to restore to it's younger self.*

 TIMER

Anti-aging

BRAIN

Brain Health

BENEFIT

Restore & Protect

Joint

Reduce Inflammation

Booster

NAD3 is made from 3 completely natural ingredients. The key to NAD3 efficacy is due to a perfect balance of all three. Each ingredient is independently tested for purity and potency. This is the first of many 3rd party testing.

Banned Substance Control Group MakingSupplements Safe For All Athletes

Every batch is independently tested by the respected BSCG (Banned Substance Control Group). This approval allows us to work with every professional athlete in the world.

Good ingredients

This 30 day supply uses veggie capsules which are organic, vegetarian, and vegan friendly. Made in a state of art manufacturing and independently tested by the BSCG. To ensure you get the absolute best product that will continue to work, we perform 6 months, 1 year, and 2 year stability testing. No other supplement company does this. But we do.

Made In USA

HPN products are manufactured in certified cGMP facilities located in the United States with components of global and domestic origin.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

NAD Platinum Grade Omega Platinum Grade Omega Platinum Grade Omega PA Platinum Grade Omega
Customer Reviews
4.3 out of 5 stars
3,791
4.1 out of 5 stars
77
4.3 out of 5 stars
136
4.3 out of 5 stars
33
4.3 out of 5 stars
1,590
4.0 out of 5 stars
131
Price $38.95 $27.99 $69.99 $39.99 $54.85 $47.99
WHAT: Anti Aging NAD+ Booster Sirtun Booster Ultra Pure Trans-Resveratrol Natural Test Booster CBX Clark Bartram Series Platinum Grade Omega-3 mTOR Elevation Metabolism Optimization
WHEN: Take 2 capsules daily, when you first wake up or before your first meal. Take 1 capsule before bed, preferably 30 minutes after consuming your last meal. Take 3 capsules upon waking. Usage of T(5) should be cycled in a pattern of 6 days ON and 1 day OFF. Choose a consistent day of the week for your day OFF. Take 3 softgels all at once with a meal or spread throughout multiple meals. Take 5 capsules 30 minutes to 1 hour before your daily workout or training session. Usage of PA(7) Should be cycled in a pattern of 6 days ON 1 day OFF. Take 2 capsules upon waking up before your first meal or before exercise.
WHY: Improve Cellular Efficiency By Restoring Degrading Cellular Properties Protect And Repair Your DNA Structure, Reduce Cellular Inflammation, Improve Your Cardiovascular And Metabolic Health Testosterone is responsible for increasing muscle mass. Leaner body mass helps control weight and increases energy Increase Joint, Brain, Heart Health and Muscle Growth GET STRONGER 50% more muscle gained than the average placebo Super Charge Your Metabolism & Burn Fat
NSF For Sports:

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Package Dimensions ‏ : ‎ 4.57 x 2.44 x 2.44 inches; 2.47 ounces
  • Item model number ‏ : ‎ 9649671
  • Date First Available ‏ : ‎ June 20, 2014
  • Manufacturer ‏ : ‎ HPN
  • ASIN ‏ : ‎ B00L5Q951S
  • Customer Reviews:
    4.3 4.3 out of 5 stars 3,791 ratings

Compare with similar items

This Item
HPN NAD+ Booster (NAD3), Anti Aging Cell Booster, NRF2 Activator, Nicotinamide Riboside Alternative, NAD Supplement Natural Energy, Longevity, and Cellular Health, 312 Mg per Serving (1 Month Supply)
HPN NAD+ Booster (NAD3), Anti Aging Cell Booster, NRF2 Activator, Nicotinamide Riboside Alternative, NAD Supplement Natural Energy, Longevity, and Cellular Health, 312 Mg per Serving (1 Month Supply)
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Price$38.95-35% $44.99
Typical:$68.99
$34.95$27.95-36% $44.99
List:$69.99
-12% $35.50
Typical:$40.46
Price Per Unit$0.65 / Count$0.50 / Count$1.17 / Count$0.31 / Count$0.56 / Count$1.18 / Count
Delivery
Get it as soon as Wednesday, Jan 15
Get it as soon as Wednesday, Jan 15
Get it as soon as Wednesday, Jan 15
Get it as soon as Wednesday, Jan 15
Get it as soon as Wednesday, Jan 15
Get it as soon as Wednesday, Jan 15
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Important information

Ingredients

Active Ingredients: Wasabia Japonica, Theacrine, Cuprous Niacin - 311mg

Directions

Take 2 capsules per day upon waking or immediately prior to your first meal

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

4.3 out of 5 stars
3,791 global ratings

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Customers say

Customers find that the nutritional supplement provides them with more energy and mental clarity. They find it delivers on its health promises, providing a boost to mitochondria and healthier cells. Many of them feel better and less aches and pains. The product reduces inflammation and improves cognition.

AI-generated from the text of customer reviews

385 customers mention "Value for money"309 positive76 negative

Customers like the nutritional supplement for its value for money. They say it's a quality product that delivers on its health promises. Some report feeling stronger, better, and stabilized after taking it. The AMPK activator helps support stamina and endurance, and some minor health issues have stabilized.

"My experience after 2 months taking it, it’s very good. The lines around my eyes and mouth are literally fading and I am more energetic." Read more

"Great Deal" Read more

"...Improved performance, overall feel, endurance. Thank you!." Read more

"Great product" Read more

274 customers mention "Energy level"261 positive13 negative

Customers appreciate the nutritional supplement's energy level. They report it gives them more energy and mental clarity, allowing them to focus better and feel less hungry overall. The long-lasting stimulation of the adrenaline seems pretty striking, and they have significant improvements in their cardio and resistance training. Some also mention vivid and pleasant dreams.

"...The lines around my eyes and mouth are literally fading and I am more energetic." Read more

"I feel like this had good effect on my energy level during the day...." Read more

"...Much better. I still feel energetic--and optimistic--but am not completely exhausted hours later after the initial burst of energy has waned...." Read more

"...My sense of smell was greatly enhanced and I started having vivid and pleasant dreams. A bounce returned to my step. I felt decades younger...." Read more

150 customers mention "Benefits"135 positive15 negative

Customers enjoy the nutritional supplement's benefits. They say it provides an added boost to mitochondrial health, resulting in healthier cells. The supplement keeps customers mentally alert and full of energy, with no side effects. It also promotes mitochondria communication, which helps joints.

"...is the only active ingredient in this product is an extremely important advance in anti-aging, though I'm skeptical of many of the ad-copy-like or..." Read more

"...believe that taking it for a longer period of time improves the functions all your body's organs and such...." Read more

"This supplement is excellent! I'm already on my third bottle, and I highly recommend it." Read more

"...Theacrine is an interesting ingrediant...." Read more

114 customers mention "Feel better"103 positive11 negative

Customers are satisfied with the nutritional supplement. They report feeling better, with more energy and alertness, less muscle aches and pains, softening skin, and improved skin elasticity. Some find it helpful for arthritis.

"...I don't know why, but it is gone and I am feeling great. I always take resveratrol daily, and many other supplements as noted above...." Read more

"...I guess it was a good feeling and overall I feel pretty good on Niagen. I'm not really sure if it did much, but I think it did...." Read more

"...Improved performance, overall feel, endurance. Thank you!." Read more

"...I feel more rested and energized in the morning as well and I find that I am dreaming again...." Read more

97 customers mention "Focus"93 positive4 negative

Customers appreciate the product's focus. They report more energy and mental clarity, as well as a better mood. Some also mention that their night vision has improved and their eyesight started improving in fall 2016.

"...various situations for a week, I have concluded that my night vision has greatly improved...." Read more

"...I saw how I have more energy and also have been very focused. I will post an update on how I feel as the weeks go on...." Read more

"...few months now and have really noticed a difference in the way my brain comprehends and processes thoughts...." Read more

"No doubt about the increase in energy and mental focus. What is doing it? Is it the Wasabia japonica?..." Read more

49 customers mention "Sleep quality"42 positive7 negative

Customers find the nutritional supplement improves their sleep quality. They report more energy, restful sleep, and improved attention and cognitive functioning.

"...The fatigue is mostly dissipated, and I believe will dissipate completely in the next day or two...." Read more

"...I even threw a few sprints in during my run, but I could not get tired at all. Not even close. It was the weirdest feeling in my life...." Read more

"...things that I couldn't find time to do forever and that I am not tired!..." Read more

"...Results: I find I sleep better in general. I do not notice any kind of big energy rush like coffee or an energy drink, not even once...." Read more

45 customers mention "Skin ageing"42 positive3 negative

Customers are satisfied with the nutritional supplement's effects on skin ageing. They report a small improvement in skin complexion and feel more energized and youthful after using it.

"...A bounce returned to my step. I felt decades younger. But the effect went away after about two years...." Read more

"...started taking this product for anti aging and I really feel my skin getting better after taking it...." Read more

"really helps me look younger." Read more

"...I feel like this product has definitely slowed down the aging process for me, and people I first meet often think I am 5 to 10 years younger than..." Read more

44 customers mention "Stomach discomfort"19 positive25 negative

Customers have different experiences with the nutritional supplement. Some find it helps them feel good and mentally sharper, giving them a bit of pep in their step. Others report stomach issues like heartburn, headaches, nausea, and vomiting.

"This product over three weeks caused everything I ate to give me stomach issue and terrible heartburn. I tried to return this product but says..." Read more

"...supplement is not about feeling super energetic all the time, feeling like a superhero...." Read more

"Tried this. Two days in the worse headache developed and then the nausea and vomiting. Stopped it for a few days and everything stopped...." Read more

"...of nutrient the aging process will be much more tolerable and enjoyable." Read more

Feeling great again on NAD3
5 out of 5 stars
Feeling great again on NAD3
I am 58 years old, in good health and work out and run regularly. As I continue to get older, I noticed that I just wasn't a sharp as I had been, multi tasking seemed harder and my focus and concentration wasn't what it used to be. My memory was also getting worse. I started taking this product back when it was Niagen and saw some great improvements. The improvements were subtle but continuous. Better memory and better concentration at work. Recently I changed to NAD3 and I'm now on my second bottle and have seen even better improvements. The best way I can explain it is my mental fog has gone away. At work, I have much more focus and get more done. My memory is better and I'm not searching for my words. I take the recommended dose of 2 pills first thing when I wake up in the morning. I love all the health and anti-aging benefits that is happening in the background, but even more I love the way I feel sharp again. Great product!
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Top reviews from the United States

  • Reviewed in the United States on October 19, 2024
    My experience after 2 months taking it, it’s very good. The lines around my eyes and mouth are literally fading and I am more energetic.
    22 people found this helpful
    Report
  • Reviewed in the United States on September 16, 2024
    I tried it-I felt the physical difference-I have and will repeat orders. Improved performance, overall feel, endurance. Thank you!.
    19 people found this helpful
    Report
  • Reviewed in the United States on October 31, 2024
    I feel like this had good effect on my energy level during the day. I know the effects are more cellular, but I think it makes a difference over time. Will continue to order.
    One person found this helpful
    Report
  • Reviewed in the United States on April 30, 2015
    I am a 65 year old female who has had cancer twice, and have been in remission from stage 4 metastatic cancer for 11 years, due in part I believe to a regimen of supplements including resveratrol, quercetin, Vitamin C, Vitamin D3, and many others. I also walk 3 miles per day, and have tried to avoid sugar and refined carbs for much of that time.

    Throughout the years I have been following anti-aging and anti-cancer research, as a curious layperson. I have explored writings and videos by David Sinclair of Harvard, Leonard Guarente of MIT, and others, leading me to the recent reports on the postulated benefits to humans of NAD precursor, Nicotinimide Riboside. Leonard Guarente himself takes it, according to his Elyseum website.

    I started taking the recommended dose in early February, 2015, and can report some positive results, although I believe the dosage level is critical and probably varies widely, depending on one’s age and health status.

    My experience has been that the prescribed dose of 250 mg. is simply too much. It revved me up, but the rebound effect was very noticeable--exhaustion. A suitable analogy might be constantly gunning and red-lining one’s old, inefficient engine. So I cut back to a half dose every other day. Much better. I still feel energetic--and optimistic--but am not completely exhausted hours later after the initial burst of energy has waned.

    It would certainly seem logical that younger, healthy, and/or athletic folks already have sufficient amounts of NAD, so they probably wouldn't notice much if any improvement from supplementation with NR. However, old folks have NAD deficiency as a result of aging, and probably see a much greater benefit from supplementation with NR. which increases NAD.

    I am guessing that most of the folks reporting little or no benefit from NR are either younger & healthy and have plenty of NAD; or, perhaps are taking far more than they need, producing some sort of negative hormesis-like response; or are not taking complementary doses of resveratrol, or other pterostilbenes, which operate in tandem with NAD as a substrate to influence anti-aging sirtuins.

    An update:
    I am now 68 and still taking NR from various makers, who add various components along with NR (all Niagen based) and at various dosages.. The 250 mg. dose is now my standard, however, and I no longer have the exhaustion effect. I don't know why, but it is gone and I am feeling great. I always take resveratrol daily, and many other supplements as noted above.
    I am also considering the other NAD precursor which is starting to become available, nicotinamide mononucleotide, but the price has got to come down significantly and some major advantage over NR demonstrated.
    Another possible effect from taking the 250 mg. NR dose is noteworthy: my fasting blood sugar is now running in the 60's and 70's regularly, but I do not feel bad. I have been doing a form of intermittent fasting for some time, but even when I have a regular meal, a few hours later my fasting glucose is back in the 60's & 70's. I test it daily. This may in fact serve as a long-term indicator of the continued efficacy of NR. I have never had fasting glucose levels this low, before taking 250 mg. of NR daily.
    753 people found this helpful
    Report
  • Reviewed in the United States on November 3, 2024
    Great Deal
    One person found this helpful
    Report
  • Reviewed in the United States on July 30, 2024
    Perhaps my expectations were too high and my body chemistry is too tolerant of certain supplements…with that disclaimer in mind I didn’t feel much with these pills. It had a very minimal effect on my mind/body, if any. I was hoping for some clarity and energy and think I may have felt a hint of pep, I think. That being said and to be fair to the brand, I do have an above normal tolerance for supplemental lifts but no sparks on this one.
    12 people found this helpful
    Report
  • Reviewed in the United States on November 26, 2024
    I feel like this product has really helped my memory. It did take time before I started noticing an improvement, but I can definitely tell a difference. I am in my 70's
    5 people found this helpful
    Report
  • Reviewed in the United States on January 14, 2020
    My story may be of interest to many who are tempted by this product. I started taking HPN Niagen plus pterostilbene about three years ago and noticed an uplift in energy after the first week. My sense of smell was greatly enhanced and I started having vivid and pleasant dreams. A bounce returned to my step. I felt decades younger. But the effect went away after about two years. I read this can happen and so took TMG for methylation support. Nothing... Recently I read David Sinclair's books, watched his podcasts and started taking NMN and micronized Resveratrol. In a few days, my acute sense of smell returned and I felt fabulous. I was about to toss my remaining bottle of HPN's Niagen. First I wanted to check on how much Niagen I had been taking for the last year. To my dismay, the answer was zero! So I started reading online and learned that Chromadex, who had originally supplied HPN with Niagen, quit doing so in December 2018. This was because of a complicated lawsuit Chromadex has with Elysium, the company which sells Basis. At any rate, Chromadex, now sells Niagen directly to consumers and no longer to third parties. Their product is called Tru-Niagen. I am truly astonished that HPN did not inform its customers of the important change in formulation. Their current bottles look identical to those I purchased three years ago. You would have to read very small print to see that Niagen is no longer included. So when the company calls posts like this scams, do not believe them. They are cheating you. You can read up on this yourself and verify that Chromadex stopped selling Niagen to HPN in December 2018. There are zero studies validating their replacement formulation, but lots of claims in their advertising. They must have enjoyed a few years of high ratings and great reviews and did not want to see an end to it. Walk away!
    147 people found this helpful
    Report

Top reviews from other countries

  • Natasha Derbas
    5.0 out of 5 stars Good product
    Reviewed in the United Arab Emirates on November 20, 2023
    Works well
  • Jarsel
    1.0 out of 5 stars This is not NAD+ this is NAD3
    Reviewed in the United Arab Emirates on January 2, 2025
    Confusing advertising!!!!!! why the write NAD this have nothing to do with nAD + not even the ingredients 👎👎👎👎👎
  • Lee
    5.0 out of 5 stars Excellent
    Reviewed in Australia on June 11, 2020
    Great quality,good value.
  • Mohamed Alhashimi
    1.0 out of 5 stars Horrible smell
    Reviewed in the United Arab Emirates on March 31, 2024
    Has a horrible scent to it like it’s something rotten
  • Aybeniz salmanova
    1.0 out of 5 stars No wffect
    Reviewed in the United Arab Emirates on October 19, 2023
    Felt more tired useless

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