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3M ESPE 12105F PerioMed 0.63% Stannous Fluoride Oral Rinse Concentrate Refill, Tropical Fruit Flavor, 10 oz. Bottle with Pump
Purchase options and add-ons
- Stannous fluoride 0.63% aids in the prevention of dental decay
- Antimicrobial action helps control plaque bacteria for up to 8 hours
- Great flavor helps to assure compliance with treatment
- Promotes oral health in people with gingivitis
- Remineralization effect builds increasing protection against painful tooth sensitivity over time
- Stannous fluoride provides antimicrobial activity for up to 8 hours
- Does not contain alcohol
- Costs about the same as the leading over-the-counter mouthwashes
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Product details
- Is Discontinued By Manufacturer : No
- Package Dimensions : 6.97 x 2.64 x 2.56 inches; 12.31 ounces
- Item model number : 70201054122
- Date First Available : April 30, 2014
- Manufacturer : 3M
- ASIN : B00K5HV05C
- Best Sellers Rank: #4,329 in Industrial & Scientific (See Top 100 in Industrial & Scientific)
- #2 in Fluoride Gels & Foams
- Customer Reviews:
Product Description
PerioMed™ 0.63% Stannous Fluoride Oral Rinse Concentrate is an antimicrobial rinse and an integral part of an effective oral health regimen. When combined with a professional treatment program, PerioMed is an effective aid for those that need help controlling:
- Gingivitis
- Tooth decay
- Dental Hypersensitivity
- Plaque formation
Advantages of Stannous Fluoride
Fluoride is a mineral that works by making the teeth stronger and more resistant to decay caused by acid and bacteria. The most common form of fluoride is sodium fluoride, used in most over-the-counter toothpastes and mouthwash products containing fluoride. Stannous fluoride, the active ingredient in PerioMed, has antibacterial properties; less bacteria means less acid byproduct. But it also helps to convert the tooth mineral hydroxyapatite into fluorapatite, which fortifies the enamel against acid attacks. Stannous fluoride remains active for up to 8 hours, providing antimicrobial activity and strengthening tooth enamel.
About 3M ESPE
For more than a century, people worldwide have looked to 3M for new products and ideas that solve everyday problems and make their lives easier and better. For decades, hospitals, clinics, and laboratories have trusted 3M as a dedicated partner supplying essential products designed to meet the unique needs of health professionals, thereby contributing to the advancement of better health practices, outcomes, and quality of care. As an innovative part of 3M Healthcare, 3M ESPE markets more than 2‚000 dental products and services that improve the practice and delivery of effective patient oral care.
Important information
Legal Disclaimer
3M industrial and occupational products are intended, labeled, and packaged for sale to trained industrial and occupational customers for workplace use. Unless specifically stated otherwise on the applicable product packaging or literature, these products are not intended, labeled, or packaged for sale to or use by consumers (e.g., for home, personal, primary or secondary school, recreational/sporting, or other uses not described in the applicable product packaging or literature), and must be selected and used in compliance with applicable health and safety regulations and standards (e.g., U.S. OSHA, ANSI), as well as all product literature, user instructions, warnings, and other limitations, and the user must take any action required under any recall, field action, or other product use notice. Misuse of 3M industrial and occupational products may result in injury, sickness, death, or property damage. For help with product selection and use, consult your on-site safety professional, industrial hygienist, or other subject matter expert. For additional product information, visit www.3M.com.
Top Brand: 3M
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Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers find this mouthwash effective for maintaining good dental health and preventing gum disease. They appreciate its value for money, functionality, and pleasant taste. Many find it easy to use and say it helps with dental hygiene. However, some customers have mixed opinions on the quality.
AI-generated from the text of customer reviews
Customers appreciate the product's benefits for teeth and gum health. They say it helps heal mouth sores, prevent cavities, and fight gum disease. Many customers have used it for years without any issues with their gums or teeth.
"...for 20 years no problems with my gums or teeth" Read more
"...Used with normal brushing and flossing will help keep teeth and especially gums healthy (should help keep gums looking pink and healthy)...." Read more
"...It helped mitigate tooth sensitivity and tooth decay before I got my wisdom teeth removed. The bottle is easy to use...." Read more
"...I started using this more than 20 years ago and still have my own teeth 😬 what a remarkable product, it helps with infection and keeps your gums..." Read more
Customers appreciate the product's value for money. They say it's a good item at half the price and a great addition to their daily routine.
"...All in all this is a great product that’s being sold at a fraction of the price at the dentist office." Read more
"Good stuff. What my dentist uses. Fair price. Get it lol" Read more
"Use thus for heathy teeth. Great product!!!!!" Read more
"This was recommended by my dentist as the best-priced and most-efficient stannous fluoride wash...." Read more
Customers like the product's functionality. They say it works well for their dental needs, has a mild fruit taste, and effective sodium fluoride. The mouthwash gets rid of many issues with gums.
"This mouthwash truly got rid of many of the issues that I had with my gums...." Read more
"Easy to use and seems to be working just fine.8" Read more
"The pump does not work, luckily I can use the pump from a prior bottle. The product is excellent. Delivery was late." Read more
"...His doctor recommended this product to us and it really works so well I bought it again. I will always continue buying this product." Read more
Customers find the taste pleasant.
"...It does not have an unpleasant taste whatsoever and in follow-up examinations it’s clearly functioning as it should indicating its high-quality...." Read more
"My dentist recommended this product, so I use it. It tastes okay and I receive it promptly...." Read more
"...- no instructions included .. liquid fluoride is quite viscous.. tastes good." Read more
"...The taste does not bother me though might to some." Read more
Customers like the mouthwash. They say it helps clean their mouth, teeth, and gums, disinfects gums well, and helps with dental hygiene. It cleans better than floss and kills unwanted bacteria. The rinse container is straightforward and easy to use, but it can crack if dropped. Overall, customers find it effective in cleaning their mouth and reducing tooth staining.
"This was recently recommended for me for general oral health, including my gums...." Read more
"This product tastes nice and seems to clean well. How much effectiveness the fluoride treatment provides will take several months to know." Read more
"...It does, however, stain teeth." Read more
"...The bottle is easy to use. The rinse container is straightforward and easy to use, but it can crack if dropped or handled roughly." Read more
Customers find the product easy to use and say it has a good flavor. It's also good for their gums.
"Easy to use. But the bottle leaks. It leaks through the pump spring you use to fill the little cup. Product is "self-wasting"" Read more
"...The bottle is easy to use. The rinse container is straightforward and easy to use, but it can crack if dropped or handled roughly." Read more
"Easy to use and seems to be working just fine.8" Read more
"This is a great fluoride treatment. Was a really good deal and easy to use. Really makes my teeth feel strong!" Read more
Customers appreciate the dental protection the product offers. They mention it's used to protect gums, cavities, and periodontal health. The regular care product provides added protection and prevents dental caries.
"The reason for this item is to prevent dental caries." Read more
"Taste is fine, used to protect gums." Read more
"...This is a product to use for cavity protection and periodontal (gum) health!..." Read more
"Whatever It Takes to Protect Your Teeth..." Read more
Customers have mixed opinions about the product quality. Some find it authentic and good, while others say it's self-wasting and impossible not to rinse.
"...The bottle is durable, however that’s not really a deciding factor for me as it does not leave the bathroom counter...." Read more
"Original quality delivered on time" Read more
"...Product is "self-wasting"" Read more
"Good product" Read more
Reviews with images

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Top reviews from the United States
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- Reviewed in the United States on October 7, 2024It used to be, you could not purchase this product without a prescriiption from a Dentist. I been using it for over 20 years. I am a older peerson and have all my teeth. After you brush at night, take a small paper cup add only one squirt from the pump of this product, one time hitting the pump , to the smallest amount of water, take it all at once into your mouth rinse it for one minute. Do not eat for one hour, this is the reason I used it at night . You will have no cavities, or bleeding gums, fantastic invention. for 20 years no problems with my gums or teeth
- Reviewed in the United States on February 14, 2025This was recently recommended for me for general oral health, including my gums. It does not have an unpleasant taste whatsoever and in follow-up examinations it’s clearly functioning as it should indicating its high-quality. It is quite thick, however, you are to dilute it with water before rinsing your mouth. The bottle is durable, however that’s not really a deciding factor for me as it does not leave the bathroom counter. All in all this is a great product that’s being sold at a fraction of the price at the dentist office.
- Reviewed in the United States on June 28, 2024This mouthwash truly got rid of many of the issues that I had with my gums. Granted, I still had to go to the dentist to actually get proper care, but rinsing with it was a big help since I wasn't able to afford an appointment for some time. The nozzle is not the best, I feel like I wasted some of it a few times, but over time I got better at calculating the amount per pump so I could make it last longer. Wish it was more readily available for everyone, looking forward for it to come back to stock since the last one is almost done
- Reviewed in the United States on November 8, 2024My dentist recommended this product, so I use it. It tastes okay and I receive it promptly. The only problem is the pump, some work okay and some leak and dribble after you use it. I’ve learn to keep the old one if if was working okay and reuse it if needed.
- Reviewed in the United States on February 13, 2025Good stuff. What my dentist uses. Fair price. Get it lol
- Reviewed in the United States on October 26, 2024Dentist recommended and used for many years. The container has the convenient pump dispenser. The liquid is thick and stirring in water is needed. Used with normal brushing and flossing will help keep teeth and especially gums healthy (should help keep gums looking pink and healthy). Great for after a dental work to help healing. Highly recommend.
- Reviewed in the United States on March 1, 2025Always pleased with this product
- Reviewed in the United States on November 9, 2024It arrive on time and the produ t was exactly what I ordered!