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The Best Cat Flea And Tick Medications

January 25

We've done the research and compiled a list of the best Cat Flea And Tick Medications on the market. So, whether you're looking for the best value, the best features, or the best performance, we've got you covered.

30-day money back FREE delivery* Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

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Frontline 20% Off

30-day money back FREE delivery* FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs., 3 Treatments

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30-day money back FREE delivery* PetArmor Plus for Cats, Flea & Tick Prevention for Cats Over 1.5 lbs, Waterproof and Fast-Acting Topical Flea and Tick Medication, (1, 3, 6, 12) Months of Treatment, (1, 3, 6, 12) Count

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Frontline 13% Off

30-day money back FREE delivery* FRONTLINE® Gold for Cats Flea & Tick Treatment (Cats over 1.5 lbs.) 6 Doses

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TevraPet 36% Off

30-day money back FREE delivery* TevraPet FirstAct Plus Flea and Tick Prevention for Cats Over 1.5lbs, 6 Monthly Doses, Topical Drops

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Advantage 17% Off

30-day money back FREE delivery* Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 6-Month Supply

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Advantage 45% Off

30-day money back FREE delivery* Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 6-Month Supply

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Cheristin 17% Off

30-day money back FREE delivery* Cheristin for Cats Topical Flea Prevention – Starts Killing Fleas in 30 Minutes, 6 Dose

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PetArmor 14% Off

30-day money back FREE delivery* PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses

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30-day money back FREE delivery* TevraPet Actispot II Flea Treatment for Large Cats 9+ lbs | 6 Doses | Powerful Prevention and Control

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Best in 2025

Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

Exceptional

9.8 Our Score

30-day money back FREE delivery*

FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs., 3 Treatments

Excellent

9.5 Our Score

30-day money back FREE delivery*

PetArmor Plus for Cats, Flea & Tick Prevention for Cats Over 1.5 lbs, Waterproof and Fast-Acting Topical Flea and Tick Medication, (1, 3, 6, 12) Months of Treatment, (1, 3, 6, 12) Count

Excellent

9.2 Our Score

30-day money back FREE delivery*

FRONTLINE® Gold for Cats Flea & Tick Treatment (Cats over 1.5 lbs.) 6 Doses

Very Good

8.9 Our Score

30-day money back FREE delivery*

TevraPet FirstAct Plus Flea and Tick Prevention for Cats Over 1.5lbs, 6 Monthly Doses, Topical Drops

Very Good

8.7 Our Score

30-day money back FREE delivery*

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Our Best Cat Flea And Tick Medications for 2025

30-day money back FREE delivery* Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

View Deal Check on Amazon

Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs., 3 Treatments

PetArmor Plus for Cats, Flea & Tick Prevention for Cats Over 1.5 lbs, Waterproof and Fast-Acting Topical Flea and Tick Medication, (1, 3, 6, 12) Months of Treatment, (1, 3, 6, 12) Count

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Cat Flea And Tick Medications